Archive for the ‘Uncategorized’ Category
Diabetes – Avoid Fatty Food
The disproportionate use of fat in meals has been related to the development of diabetes. Recent studies at a reputed Health Science Center, established that consumption of an extra forty grams of fat per day amplifies the chances of developing diabetes by three times. A diet that is rich in fat, particularly one saturated with animal fat, seems to damage the effect of insulin. Researchers calculated the saturated fatty acids in the muscles cells of older non-diabetic men and the women that were about to have surgery and found that higher the occurrence of saturated fatty acids in the cells, the higher the insulin resistance. In contrast, higher tissue levels of polyunsaturated fats, predominantly fish oil, indicated better insulin activity and lower resistance. Fish oil differs from animal fats in that fish oil contains polyunsaturated fatty acids. One of the fatty acids called omega-3 is especially good for the heart—it lowers cholesterol and protects from atherosclerosis. As a matter of fact, the folks conducting the research also noted that the consumption of omega-3 fish oil successfully overcame their insulin resistance.
In another study, researchers considered and the eating habits and insulin activity among forty five non-diabetic women and men. One half of them were obese and the other half of normal weight. Higher fat consumption increased insulin resistance in both groups. This indicates, said the researchers that even normal individuals who lower their insulin efficiency tend to become vulnerable to diabetes.
Diabetes – Avoid Meat and Meat Products
“Eat Less Saturated Fat” happens to be one of the most vital nutrition guidelines to follow. A fast and easy way to do that is to refrain from eating meat and meat products. Meat is high both in saturated fat and cholesterol. Folks with diabetes have a bigger risk of heart disease in the early stages of life. The practically useless calories combined with saturated fats lead to lots of extra body weight and obesity, This puts a person with diabetes at a greater risk of heart disease.
When it comes to diabetes, meat is quite harmful. Meat increases the toxemic condition underlying the diabetic state and reduces glucose tolerance. The meat from animals increases the burden on the
Managing diabetes in the approved manner is highly important. The methods and means to manage diabetes efficiently are progressively evolving. The most up-to-date medical and scientific advances—Including ones involving Internet a medical advice column or a reputed diabetes blog—have begun providing the millions of people around the globe that are affected by this disease, with the kind of freedom only a few dreamed of a while back.
Diabetes is a chronic condition which prevents the body from efficiently metabolizing sugar into the energy we need to function. When we consume a meal, the body breaks the food down into a number of nutrients counting a sugar called glucose, which happens to be the main source of energy for the body. Glucose is carried in the bloodstream to all cells where it is used for fuel to produce energy. Glucose cannot pass into cells lacking the help of a hormone called insulin. Insulin is necessary to convert glucose into energy. Since over time the high blood sugar levels associated with diabetes- one of the worlds-leading cause of death by disease-can lead to complications of the eyes, blood vessels, nerves, kidneys and other organs, anything that would ease the typical daily regimen of insulin injections and the like would be most welcome by patients.
Much unlike in the past, the newest advances, treatment and disease management suggestions and advice are now available on the websites of a number of diabetes associations and countless others. What’s more is that, the availability and the convenience of being able to order the necessary diabetic supplies, medicines and equipment online make managing diabetes a whole lot easier than it was in the days gone by.
Diabetes Management – Maintain your schedule
An hour or so after you eat is when your blood sugar is at its highest, after which it begins to drop. This predictable pattern can work to your benefit. If you have your meals at the same time you can minimize the amount of change in your blood sugar levels, eat five or six small meals or eat healthy snacks at regular times in between your meals.
Diabetes Management – Keep an eye on your blood sugar level
For a person with diabetes, at least a moderate amount of exercise is required if not more. But, it is important to remember to check your blood sugar level before, during and after your exercise, particularly if you take insulin or medicines that are meant to lower blood sugar.
Some Tips to Manage Diabetes
• Keep a fixed exercise timetable.
• Do not eat straight away after you exercise
• Keep your weight under control
• Match your mealtime plan to your insulin schedule
• Maintain a Healthy Diet to Control Diabetes
is defined by experts in the field of psychiatry as a psychological disorder characterized by extended periods of sadness and melancholy and, quite often, unpredictable behavioral quirks.
A person who’s going around with a long face and being cheesed off with the world in general may not necessarily be suffering from clinical depression, as there’s bound to be bad moods now and then. However, if a morose and mirthless disposition, low self-worth and lack of happiness become routine, then it could prima facie be a case of clinical depression
That, of course, would be a very broad diagnosis which can be narrowed down further as per symptoms. There’s, for instance, manic or bipolar depression: it is characterized by extreme and unpredictable mood swings such that a person may be euphoric today and morose tomorrow without any apparent reason. Postpartum depression ails new mothers and is just a prolonged period of sadness, possibly as a result of exceptional physical stress during childbirth or an uncertain sense of responsibility toward the newborn.
Some other noteworthy forms are:
- Dysthimia is a less severe form of depression in which the symptoms are somewhat less pronounced, but the treatment should be done without any delay whatsoever.
- Seasonal Affective Disorder is characterized by falling in a rut during a particular season, i.e. winter, spring or summer. Mood swings may also happen during a specific season.
Hard to deal with as its sounds, clinical depression is far from incurable. Quite to the contrary, doctors are fairly positive regarding chances of recovery. The majority are of the opinion though that the best results are had when clinical depression is detected early and attended to immediately. Patients who’ve accepted their condition and actively sought treatment have invariably found themselves improving vis-à-vis the aforementioned condition. Left untreated, clinical depression can not only lead to violent, often self-destructive behavior, but the high degree of mental stress involved can also give rise to seemingly complications such as hypertension and diabetes.
Questions regarding clinical depression may be as basic as ‘do I have it’? Any or all questions you may have must be addressed to a professional. The temptation for a quick referral by reading journals or websites may be tempting but relying on these without professional help is strictly not advised. Self-medication could be very dangerous, so even if you’re aware of some of the medicines prescribed for your condition, please do not self-medecate. Clinical depression is best handled quickly and professionally so you can lead a better life.
Nearly 90% of cases of type 2-diabetes could be solved by changes in lifestyle simple. In this case, it is important to think about prevention, because diabetes is very difficult to treat and some medicines used to do so can have serious side effects include cardiovascular system.
Type 2 diabetes is on the verge of becoming a national epidemic. In a report published in December 2009, said the Canadian Diabetes Association, the number of Canadians living with diabetes has doubled between 2000 and 2010, jumping from 1.3 to 2.5 million people.
Even worse, it is estimated that between 2010 and 2020, 1.2 million new diabetes cases will be diagnosed, bringing the number of people fighting this disease to nearly 3.7 million. According to the Diabetes Association, this is a “economic tsunami” as costs associated with the disease could reach $17 billion by 2020.
The damage caused by type 2 diabetes is due to the numerous problems stemming from chronic hyperglycemia: a higher risk of cardiovascular disease and some cancers, renal insufficiency, retinopathy, circulation problems in the lower limbs and even serious cognitive issues like Alzheimer’s Disease. Diabetes is not a “benign” disease, as is thought to be the case by many. It is, in fact, a very serious health problem that could lead to serious health consequences to the afflicted.
The danger posed by type 2 diabetes remains high, as the disease continues to be very hard to treat. In fact, despite advances in medicine, the available treatment options are relatively minimal, and the available medications can have serious side effects. The class of medications called thiazolidinedione (TZD) is a good example: even if the compounds are very useful in improving the body’s response to insulin (and thus reducing blood sugar levels), the medication can frequently cause water retention that leads to an increase in blood volume. In some cases, this retention is so significant that their blood volume is too much for the heart’s pumping system, potentially leading to major complications.
Recent studies have shown that these side effects are the result of an unexpected action by TZD on the systems involved in the re-absorption of ions and water in the kidneys. In most cells, TZD interacts with a protein called the peroxisome proliferator-activated receptor (PPAR), and this interaction stimulates the synthesis of proteins that improve response to insulin and the entry of glucose into the cells. In the kidneys, however, the interaction of TZD with PPAR causes a completely different response: there is instead a large increase in the retention of sodium and bicarbonate that leads, by the process of osmosis, to a massive entrance of water into the cells. This retention makes it so that patients treated with TZD often see significant weight gain and, in more serious cases, suffer damage to the heart.
Importance of prevention
These observations show that although medicine developed in a way that allows them to interact as specific as possible with a goal, the human genome diversity and complexity of the regulatory system in the body’s physiological make these specifications very difficult to achieve. In general, the vast majority of medications can cause side effects. Thus, although we should be happy for medical progress, which helps us to treat serious diseases, however, we must accept the limitations of these treatment options and to recognize that prevention of these diseases is as important as the treated. This concept is particularly well illustrated by the type 2-diabetes, where a healthy lifestyle based on healthy eating, healthy weights and regular physical activity can give us the opportunity to prevent 90% of cases of this disease and avoid difficulties associated with it.
What is Mosaicism?
Every cell in the human body comes from one initial cell: the fertilized egg, which is also called the zygote. After fertilization, the zygote then proceeds to divide. As new cells form, the chromosomes duplicate themselves so that the resulting cells have the same number of chromosomes as the original cell. However, mistakes sometimes happen and one cell ends up with a different number of chromosomes. From then on, all cells originating from that cell will have the different chromosomal number, unless another mistake happens. (All like cells originating from a single type of cell is called a cell line; for example, the skin cell line, the blood cell line, the brain cell line, etc.)
When a person has more than one type of chromosomal makeup, that is called mosaicism, like the mosaic style of art in which a picture is made up of different colors of tiles. In Down syndrome, mosaicism means that some cells of the body have trisomy 21, and some have the typical number of chromosomes.
How is Mosaicism Diagnosed?
The usual way in which mosaic Down syndrome is discovered is through genetic testing of the baby’s blood. Typically, 20 to 25 cells are examined. If some of the cells have trisomy 21 and some don’t, then the diagnosis of mosaicism is made. However, this blood test can only determine the level of mosaicism in the blood cell line.While mosaicism can occur in just one cell line (some blood cells have trisomy 21 and the rest don’t), it can also occur across cell lines (skin cells may have trisomy 21 while other cell lines don’t). In the latter case, it may be more difficult to diagnose mosaicism. When mosaicism is suspected but not confirmed through the blood test, other cell types may be tested: skin and bone marrow are most commonly the next cells checked. Because skin cells and brain cells arise from the same type of cell at the beginning of fetal development (ectoderm), many doctors believe that skin cell tests reflect the chromosomal makeup of the brain cells as well.
How Does Mosaicism Happen in Down Syndrome?
There are two different ways mosaicism can occur:
- The initial zygote had three 21st chromosomes, which normally would result in simple trisomy 21, but during the course of cell division one or more cell lines lost one of the 21st chromosomes.
- The initial zygote had two 21st chromosomes, but during the course of cell division one of the 21st chromosomes were duplicated.
It’s possible to determine the origin of mosaicism in individual cases using special DNA markers, but this isn’t done on a regular basis.
What Does Mosaicism Mean for my Child?
At the present time, there is not much research on the similarities and differences between simple trisomy 21 and mosaic trisomy 21. One report published in 1991 on mental development in Down syndrome mosaicism compared 30 children with mosaic Down syndrome with 30 children with typical Down syndrome. IQ testing showed that the mean IQ of the mosaic group was 12 points higher than the mean of the non-mosaic group. However, some children with typical Down syndrome did score higher on the IQ tests than some of the children with mosaic Down syndrome.The Department of Human Genetics at the Medical College of Virginia has had an ongoing study project of children with mosaic DS. In a survey of 45 children with mosaicism, they found that these children did show delayed development compared to their siblings. When 28 of these children with mosaicism were matched up with 28 children with typical Down syndrome for age and gender, the children with mosaicism reached certain motor milestones earlier than children with typical DS, such as crawling and walking alone. However, the speech development was equally delayed in both groups.
They were among the first to arrive on the scene of the World Trade Center attacks on 9/11, and many of them continued to work selflessly for months on the site, exposing themselves to airborne debris and other dangers. Now experts from Mount Sinai School of Medicine have reported that these first responders on 9/11 have heart problems, specifically impaired diastolic function of both the left and right ventricle.
Results of the new study come on the heels of a tentative settlement that would award as much as $657 million to the Ground Zero rescue and cleanup workers who were sickened by their exposure to the toxic debris at the site. In 2007, the first clinical study that connected exposure to the World Trade Center dust and serious disease released its findings.
In that study, published in Chest, it showed that the number of 9/11 responders who had a rare type of lung condition called sarcoidosis rose dramatically in the year after the attack. Other studies have shown that a high percentage of the rescue workers developed persistent coughs and other respiratory conditions, as well as psychological problems, including post-traumatic stress disorder.
Now, in a study entitled “First Documentation of Cardiac Dysfunction Following Exposure to the World Trade Center Disaster,” researchers provide evidence that the 9/11 responders have a condition in which their hearts are not able to relax normally, which increases their risk for heart failure and shortness of breath.
The study, conducted by Lori Croft, MD, assistant professor of medicine, evaluated 1,236 workers who had been part of the 9/11 rescue efforts. It found that more than 50 percent of them had impaired relaxation of the left ventricle. Among their same-age peers in the general population, this condition appears in only 7 percent of people. More than 60 percent of the participants had abnormal diastolic function in the right ventricle, which pumps blood to the lungs.
Although these study results do not definitively link exposure to debris by 9/11 responders and their heart problems, Dr. Croft and her team note that previous research indicates that inhaled debris may be associated with lung and heart disease. Additional studies are needed before the heart problems experienced by these and potentially other 9/11 responders can be connected with the disaster, but Croft points out that “these data are an exciting first step.”